The National Health Strategy (NHS) investment case used the World Health Organization's One Health Tool to estimate the cost of health services and health systems strengthening while estimating the effectiveness of health interventions using disease-specific Impact Models and the Lives Saved Tool. Technical Working Groups were set up to support the costing of the NHS, drawing membership from various organizations including the Ministry of Health and Child Care, Ministry of Finance and Economic Development, development partners, NGOs, and civil society organizations. These groups identified the interventions and activities to be costed and assisted in their prioritization.
The NHS 2021-2025 includes program-specific strategies such as the Human Resources for Health Strategy, National Infrastructure Development Plan, HIV and AIDS Strategy, Non-Communicable Disease Strategy, Mental Health Strategy, and Community Health Strategy. The strategy is anchored on the concept of an Investment Case, which outlines how the Government of Zimbabwe and its partners will efficiently save lives, improve health and nutrition outcomes, and accelerate the attainment of national goals in line with the Sustainable Development Goals.